Title page for ETD etd-10272005-155140

Type of Document Dissertation
Author Milchenko, Mikhail V
Author's Email Address mmiltc1@lsu.edu
URN etd-10272005-155140
Title Efficient Automatic Correction and Segmentation Based 3D Visualization of Magnetic Resonance Images
Degree Doctor of Philosophy (Ph.D.)
Department Computer Science
Advisory Committee
Advisor Name Title
John Tyler Committee Chair
Bijaya Karki Committee Member
Jianhua Chen Committee Member
Oleg Pianykh Committee Member
Warren Waggenspack Committee Member
Claire Advokat Dean's Representative
  • magnetic resonance
  • medical imaging
  • MR inhomogeneity
  • 3D visualization
  • segmentation
Date of Defense 2005-09-19
Availability unrestricted
In the recent years, the demand for automated processing techniques for digital medical image volumes has increased substantially. Existing algorithms, however, still often require manual interaction, and newly developed automated techniques are often intended for a narrow segment of processing needs.

The goal of this research was to develop algorithms suitable for fast and effective correction and advanced visualization of digital MR image volumes with minimal human operator interaction. This research has resulted in a number of techniques for automated processing of MR image volumes, including a novel MR inhomogeneity correction algorithm derivative surface fitting (dsf), automatic tissue detection algorithm (atd), and a new fast technique for interactive 3D visualization of segmented volumes called gravitational shading (gs).

These newly developed algorithms provided a foundation for the automated MR processing pipeline incorporated into the UniViewer medical imaging software developed in our group and available to the public. This allowed the extensive testing and evaluation of the proposed techniques.

Dsf was compared with two previously published methods on 17 digital image volumes. Dsf demonstrated faster correction speeds and uniform image quality improvement in this comparison. Dsf was the only algorithm that did not remove anatomic detail. Gs was compared with the previously published algorithm fsvr and produced rendering quality improvement while preserving real-time frame-rates.

These results show that the automated pipeline design principles used in this dissertation provide necessary tools for development of a fast and effective system for the automated correction and visualization of digital MR image volumes.

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