Title page for ETD etd-07062005-165558

Type of Document Master's Thesis
Author Bernstein, Kenneth
Author's Email Address kberns1@lsu.edu
URN etd-07062005-165558
Title ROC Comparison of Acquisition Parameters for Two PET/CT Scanners Based on Lesion Detectability in a Torso Phantom
Degree Master of Science (M.S.)
Department Physics & Astronomy
Advisory Committee
Advisor Name Title
Kenneth L. Matthews II Committee Chair
Erno Sajo Committee Member
John Tyler Committee Member
Steven Bujenovic Committee Member
Warren Johnson Committee Member
  • pet
  • lesion detectability
  • imaging
  • medical imaging
  • reveal hd
  • roc
  • discovery st
  • torso phantom
  • fdg
  • pet/ct
Date of Defense 2005-06-27
Availability unrestricted
Positron emission tomography (PET) and computed tomography (CT) are well established and powerful tools for medical diagnostics but even integrated PET/CT scanner images still lack the necessary quality and resolution that would make medical diagnoses flawless. In this thesis experiments were performed to statistically determine the effect that image acquisition parameters have upon diagnostic accuracy. Images from different PET/CT scanners were assessed by comparing subject human diagnostic accuracy from a sample of both professional and student volunteers. The assessment results were compared to the objective NEMA-standards performance data provided by the manufacturers for each scanner. The data analysis method is the receiver operating characteristic (ROC) curves. We hypothesize that human performance in making accurate diagnoses from PET images correlates with the system performance. The data shows that human diagnostic performance correlates to spatial resolution and sensitivity of the PET imaging systems.
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